Strategic investments to discover and develop new health tools, together with innovations in effectively delivering today's health tools and services, could avert 10 million deaths a year within just one generation, argue leading global health experts in a new PLOS Collection.

Linde Healthcare, a global business of The Linde Group, has announced the new beneficiaries of its REALfund initiative, a programme supporting ideas and projects with the potential to improve patient outcomes and health economics across the wide field of respiratory medicine.

To help healthcare professionals, medical researchers and the public understand the ongoing outbreak of the Zika virus, Elsevier has created a Zika Virus Resource Center on Elsevier's public news and information website. In addition, The Lancet, one of Elsevier's top medical journals, has created a Zika virus resource centre on its website,

Merck, a leading science and technology company, announces the start of its equity-free accelerator program for digital health startups. Just as the big bang shaped the universe, Merck Accelerator is looking for startups with the potential to reshape entire industries and make people's lives richer.

The search for new medicines is becoming unsustainably expensive despite huge technological advances because researchers are using the wrong methods, experts say. They say drug discovery should focus on 'validity' - how well the results of experiments predict results in sick people. Instead, it has focused on methods that are easy to industrialize or methods that are academically fashionable.

Screening large "libraries" of compounds to find those with a desired biological activity is a powerful method for discovering new drugs, but requires a large, expensive and dedicated facility. Now, scientists at the Florida campus of The Scripps Research Institute (TSRI) have devised the central component of a screening system that would be orders of magnitude smaller and cheaper.

Conducting clinical investigations of mitochondrial replacement techniques (MRT) in humans is ethically permissible as long as significant conditions and principles are met, says a new report from the National Academies of Sciences, Engineering, and Medicine.