AskBio presents 18-month Phase Ib trial results of AB-1005 gene therapy for patients with Parkinson's disease
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- Category: Bayer
The study met its primary objective, which was to evaluate the safety of a one-time bilateral delivery of AB-1005 directly to the putamen.
Next-generation treatments hitch a ride into cancer cells
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- Category: Research
Finding an effective ASO delivery system is a major challenge. Cancer cells have gatekeeper molecules that stop unwanted substances from entering.
Groundbreaking treatment approach shows promise in hard-to-treat cancers
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- Category: Research
This combined approach, developed by Florida International University cancer researcher Diana Azzam, was used successfully for the first time to guide treatment of relapsed pediatric cancer patients in collaboration with First Ascent Biomedical and Dr. Maggie Fader at the Helen & Jacob Shaham Cancer & Blood Disorders Institute at Nicklaus Children's Hospital in Miami.
This outdated diabetes drug still has something to offer
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- Category: Research
New drug prevents flu-related inflammation and lung damage
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- Category: Research
Swapping red meat for herring/sardines could save up to 750,000 lives/year in 2050
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- Category: Research
Adopting this type of diet would be especially helpful for low and middle income countries, where these fish are cheap and plentiful, and where the toll taken by heart disease, in particular, is high, say the researchers.
Does cannabis use affect cognitive decline?
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- Category: Research
The study, done by Master of Public Health (MPH) student Zhi Chen and Professor Roger Wong, Ph.D., MPH, MSW, analyzed a large data set from the CDC and found that compared to non-users, non-medical cannabis use, such as for recreational purposes, was significantly associated with 96 percent decreased odds of subjective cognitive decline (SCD).
Novel biological mechanism discovered that could lead to new treatments for neurological disorders, cancers
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- Category: Research
Dr. Ma's team found that chemical modification of RNA (called RNA methylation) regulates mitochondrial function.
New study paves the way for precision drugs to treat blood cancers
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- Category: Research
Johns Hopkins investigators develop novel treatment for T-cell leukemias and lymphomas
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- Category: Research
The therapy, an antibody-drug conjugate (ADC), combines an antibody that targets a protein called TRBC1 expressed on the surface of T-cell cancers with an anti-cancer drug, called SG3249.