Using Epo against COVID-19
- Details
- Category: Research
Erythropoietin (Epo) is actually a medication for anaemia. According to researchers at the Max Planck Institute of Experimental Medicine in Göttingen, the doping agent Epo could also be effective against COVID-19. The growth factor could mitigate severe disease progression and protect patients from long-term neurological effects when the Sars-CoV-2 virus attacks the brain.
Newer variant of COVID-19-causing virus dominates global infections
- Details
- Category: Research
Research out today in the journal Cell shows that a specific change in the SARS-CoV-2 coronavirus virus genome, previously associated with increased viral transmission and the spread of COVID-19, is more infectious in cell culture. The variant in question, D614G, makes a small but effective change in the virus's 'Spike' protein, which the virus uses to enter human cells.
Researchers identify multiple molecules that shut down SARS-Cov-2 polymerase reaction
- Details
- Category: Research
SARS-CoV-2, the coronavirus causing the global COVID-19 pandemic, uses a protein called polymerase to replicate its genome inside infected human cells. Terminating the polymerase reaction will stop the growth of the coronavirus, leading to its eradication by the human host's immune system.
Whole-town study reveals more than 40% of COVID-19 infections had no symptoms
- Details
- Category: Research
A study of COVID-19 in the quarantined Italian town of Vò, where most of the population was tested, reveals the importance of asymptomatic cases.
The authors of the new research, from the University of Padova and at Imperial College London, published today in Nature, suggest asymptomatic or pre-symptomatic people are an important factor in the transmission of COVID-19.
Even in the worst COVID-19 cases, the body launches immune cells to fight back
- Details
- Category: Research
A new study from researchers at La Jolla Institute for Immunology (LJI) and Erasmus University Medical Center (Erasmus MC) shows that even the sickest COVID-19 patients produce T cells that help fight the virus. The study offers further evidence that a COVID-19 vaccine will need to elicit T cells to work alongside antibodies.
Existing drugs can prevent SARS-CoV-2 from hijacking cells
- Details
- Category: Research
An international team of researchers has analysed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells. The research, published in the journal Cell, shows how the virus shifts the cell's activity to promote its own replication and to infect nearby cells. The scientists also identified seven clinically approved drugs that could disrupt these mechanisms, and recommend that these drugs are immediately tested in clinical trials.
Study is first to identify potential therapeutic targets for COVID-19
- Details
- Category: Research
A team from Lawson Health Research Institute and Western University are the first in the world to profile the body's immune response to COVID-19. By studying blood samples from critically ill patients at London Health Sciences Centre (LHSC), the research team identified a unique pattern of six molecules that could be used as therapeutic targets to treat the virus. The study is published this week in Critical Care Explorations.
More Pharma News ...
- Initial COVID-19 infection rate may be 80 times greater than originally reported
- Mayo finds convalescent plasma safe for diverse patients with COVID-19
- Researchers identify potent antibody cocktail to treat COVID-19
- Nanosponges could intercept coronavirus infection
- Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19
- Super-potent human antibodies protect against COVID-19 in animal tests
- Up to 45 percent of SARS-CoV-2 infections may be asymptomatic