Nearly half of COVID-19 patients left hospital in worse physical condition
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Over a year after the novel coronavirus cemented its grip on the world, much of the conversation surrounding the disease remains simple: how many people died and how many survived?
But researchers at Michigan Medicine say a devastating side effect lurks, underreported, between those extremes - the loss of ability caused by the virus.
Why are some COVID-19 vaccines working better for men than women?
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MSU researcher is studying, raising awareness about the role of sex in the efficacy of vaccines that make use of nanomedicine.
If there's one take-home message for the general public about the coronavirus vaccines approved in the U.S., it's that they are remarkably effective.
Rogue antibodies wreak havoc in severe COVID-19 cases
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The development of antibodies to the COVID-19 virus has been the great long-term hope of ending the pandemic. However, immune system turncoats are also major culprits in severe cases of COVID-19, Yale scientists report in the journal Nature.
These autoantibodies target and react with a person's tissues or organs similar to ones that cause autoimmune diseases such as lupus or rheumatoid arthritis.
COVID-19 monoclonal antibodies reduce risk of hospitalization and death
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Monoclonal antibodies, a COVID-19 treatment given early after coronavirus infection, cut the risk of hospitalization and death by 60% in those most likely to suffer complications of the disease, according to an analysis of UPMC patients who received the medication compared to similar patients who did not.
New vaccine platform: 'Two-one replicon-and-VLP-minispike vaccine' against COVID-19
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To stop the current SARS-CoV-2 pandemic, vaccines of high quality, safety, and efficacy are required. Scientists of the Paul-Ehrlich-Institut and the Ludwig Maximilian University at Munich have conceived in the laboratory a novel vector vaccine based on the vesicular stomatitis virus (VSV) with only one part of the spike protein as antigen. They have tested the characteristics of this vaccine in mice.
COVID-19 mRNA vaccines are immunogenic in pregnant and lactating women
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Pregnant women with symptomatic COVID-19 have a higher risk of intensive care unit admissions, mechanical ventilation and death compared to non-pregnant reproductive age women. Increases in preterm birth and still birth have also been observed in pregnancies complicated by the viral infection. The Centers for Disease Control and Prevention (CDC) recommended that people who are pregnant may choose to be vaccinated at their own discretion with their healthcare provider.
Major differences in COVID patient care caused by insufficient data, misleading advice
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While there was extensive use of drug repurposing throughout the first 10 months of the COVID-19 pandemic, there was substantial heterogeneity over the types of drugs used for treatment purposes globally. Some drugs, including hydroxychloroquine, saw sharp declines in use, while adjunctive therapies grew into a more relied upon method for patient management.
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