A possible new COVID-19 vaccine could be accessible for more of the world
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- Category: Research
While many people in wealthier countries have been vaccinated against COVID-19, there is still a need for vaccination in much of the world. A new vaccine developed at MIT and Beth Israel Deaconess Medical Center may aid in those efforts, offering an inexpensive, easy-to-store, and effective alternative to RNA vaccines.
Spider silk can stabilize cancer-suppressing protein
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The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now found an unusual way of stabilising the protein and making it more potent. By adding a spider silk protein to p53, they show that it is possible to create a protein that is more stable and capable of killing cancer cells.
Mutations leading to omicron variant did not enable virus to fully escape immune system
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People who gained immunity - either through vaccination or exposure - against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's omicron variant. That’s because the mutations that led to the variant’s emergence aren’t found in the regions of the virus that stimulates one type of cellular immune response,
Stealth nanomedicines combat cancer and cut toxic effects of chemo
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Nanomedicines - typically drugs hidden within nanoscopic fatty membranes ('liposomes') - have potential to transform chemotherapy treatments, improving drug delivery and reducing toxic side effects for thousands of cancer patients every year.
Now, world first research conducted by the University of South Australia has identified that the frequently used chemotherapy drug (5-FU or Fluorouracil) is 100 per cent more effective at targeting tumours (rather than surrounding tissues) when administered using an optimised liposomal formulation.
COVID-19 beliefs influenced by politicians, not scientists, researchers suggest
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As COVID-19 upended societal norms when it swept through the United States in 2020, a second pandemic - or "infodemic" - was also on the rise. An analysis of Twitter users by researchers at the University of California, Davis, and University of Texas, Austin, suggests that Republican-identifying individuals who believe their local government has positive intentions are vulnerable to believing politically fueled COVID-19 misinformation.
Scientists identify possible new treatment for COVID-19
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Investigators at Cedars-Sinai have identified a potential new therapy for COVID-19: a biologic substance created by reengineered human skin cells.
Scientists found the substance stopped SARS-CoV-2, the virus that causes COVID-19, from reproducing itself and also protected infected cells when tested in human lung cells.
New strategy for COVID-19 prophylaxis
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SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections. Researchers led by Prof. Dr. Gunther Hartmann from the Institute of Clinical Chemistry and Clinical Pharmacology at the University Hospital Bonn, in cooperation with other members of the cluster of excellence ImmunoSensation2 at the University of Bonn, have shown this in mice.
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