Fighting tumors with magnetic bacteria
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- Category: Research
Scientists around the world are researching how anti-cancer drugs can most efficiently reach the tumours they target. One possibility is to use modified bacteria as "ferries" to carry the drugs through the bloodstream to the tumours. Researchers at ETH Zurich have now succeeded in controlling certain bacteria so that they can effectively cross the blood vessel wall and infiltrate tumour tissue.
Novel derivative of "love hormone" oxytocin improves cognitive impairment in Alzheimer's
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- Category: Research
The cognitive decline and memory loss observed in Alzheimer's disease (AD) is attributed to the accumulation of β-amyloid protein (Aβ), which impairs neural function in the brain. Experimentation has shown that oxytocin, a peptide hormone primarily responsible for parturition, bonding, and lactation, also regulates cognitive behavior in the rodent central nervous system (CNS).
Why late-night eating leads to weight gain, diabetes
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- Category: Research
Northwestern Medicine scientists have uncovered the mechanism behind why eating late at night is linked to weight gain and diabetes.
The connection between eating time, sleep and obesity is well-known but poorly understood, with research showing that overnutrition can disrupt circadian rhythms and change fat tissue.
UCLA researchers identify a gene as a potential target in treatment-resistant brain cancer glioblastoma multiforme
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- Category: Research
Research led by doctors and scientists at UCLA Jonsson Comprehensive Cancer Center and the UCLA Jane & Terry Semel Institute for Neuroscience & Human Behavior have identified a gene that may provide a therapeutic target for the deadly, treatment-resistant brain cancer glioblastoma multiforme (GBM).
Protein IDs, drug candidates, show promise for COVID science
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- Category: Research
A highly innovative method using the latest technology has generated a comprehensive list of SARS-CoV-2 viral and human proteins that interact with each other, with one such interaction showing the virus directly influencing proteins that regulate the human immune system.
A new AI model can accurately predict human response to novel drug compounds
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- Category: Research
The journey between identifying a potential therapeutic compound and Food and Drug Administration approval of a new drug can take well over a decade and cost upwards of a billion dollars. A research team at the CUNY Graduate Center has created an artificial intelligence model that could significantly improve the accuracy and reduce the time and cost of the drug development process.
Possible target for treating and preventing osteoarthritis found in little-studied protein
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- Category: Research
Wear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Research have found a possible new target to fight this painful cascade.
In a study published Thursday in the journal PLOS One,biochemist Patrick Griffin, Ph.D., and colleague Mi Ra Chang, Ph.D., describe a specific protein that manages activities within chondrocytes, a critical cell type that maintains healthy cartilage in joints.
More Pharma News ...
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- Making pharmacy more sustainable
- Repurposing existing drugs to fight new COVID-19 variants
- Discovering new cancer treatments in the "dark matter" of the human genome
- Another monkey virus could be poised for spillover to humans
- Non-opioid compounds squelch pain without sedation
- Breakthrough brings potential glioblastoma drug into focus