Industry payments to physicians linked to use of some non-recommended and low value drugs among cancer patients
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Patients with cancer whose oncologist receives payments from industry appear more likely to receive some non-recommended and low value treatments, finds a US study published by The BMJ.
This finding raises potential concerns about quality of care, and the researchers say it may be appropriate to re-examine the current status of personal payments from the drug industry to physicians.
Researchers identify 'switch' to activate cancer cell death
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A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die. This new ability to trigger programmed cell death could open the door for improved cancer treatments. The findings were published Oct. 14 in the Nature journal Cell Death & Differentiation.
mRNA delivered by extracellular vesicles induces immunotherapy response in glioblastoma
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A team of researchers at The University of Texas MD Anderson Cancer Center has developed a new method for using extracellular vesicles to enhance responses to immunotherapy in glioblastoma, potentially opening the door for wider use of engineered messenger RNA (mRNA) for cancer therapy. The study was published in Nature Communications.
Americans will spend half their lives taking prescription drugs, study finds
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An American born in 2019 will spend a larger share of their lifetime taking prescription drugs than being married or receiving an education, according to new research by Jessica Ho, associate professor of sociology and demography at Penn State. She found that American males will spend approximately 48% of their lives taking prescription drugs. The number jumped to 60% for females.
New study suggests promising approach for treating pancreatic cancer
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A new study carried out in mice, led by Queen Mary University of London, has identified cells that drive the spread of pancreatic cancer and discovered a weakness in these cells that could be targeted using existing drugs. This offers a promising new approach for treating pancreatic cancer.
The research, published in Science Advances and funded by Barts Charity and Cancer Research UK, found that many patients' pancreatic cancer contains cells called amoeboid cells.
Drug-delivery technique for brain cancer shows growing promise
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A technique developed by University of Texas at Dallas and UT Southwestern Medical Center researchers to deliver medication through the blood-brain barrier has shown promise in a preclinical study for treating glioblastoma, the most common human brain cancer.
The researchers demonstrated the method in mice in a study published online Aug. 15 in Nature Communications.
Targeting a coronavirus ion channel could yield new COVID-19 drugs
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- Category: Research
The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of COVID-19.
MIT chemists have now discovered the structure of the “open” state of this channel, which allows ions to flow through.
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