Chemical in coffee may help prevent obesity-related disease
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- Category: Research
Researchers at the University of Georgia have discovered that a chemical compound commonly found in coffee may help prevent some of the damaging effects of obesity. In a paper published recently in Pharmaceutical Research, scientists found that chlorogenic acid, or CGA, significantly reduced insulin resistance and accumulation of fat in the livers of mice who were fed a high-fat diet.
Single-dose, needle-free Ebola vaccine provides long-term protection in macaques
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- Category: Research
Scientists have demonstrated for the first time that a single-dose, needleless Ebola vaccine given to primates through their noses and lungs protected them against infection for at least 21 weeks. A vaccine that doesn't require an injection could help prevent passing along infections through unintentional pricks.
Reprogrammed cells grow into new blood vessels
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- Category: Research
By transforming human scar cells into blood vessel cells, scientists at Houston Methodist may have discovered a new way to repair damaged tissue. The method, described in an upcoming issue of Circulation, appeared to improve blood flow, oxygenation, and nutrition to areas in need.
Researchers take new approach to stop 'most wanted' cancer protein
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Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have found a way to defeat one of the most tantalizing yet elusive target proteins in cancer cells - employing a strategy that turns the protein's own molecular machinations against it. In a study published online by the journal Cell, the scientists used a specially crafted compound to disrupt the protein's ability to rev up its own production and that of other proteins involved in tumor cell growth.
Best treatments for allergic conditions? Some doctors don't even know
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- Category: Research
People who suffer from allergies want to keep up-to-date on the latest information regarding treatment, but it's not always easy. Some doctors don't even know fact from fiction when it comes to treating allergies. According to a study presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, prevailing allergy myths have a long shelf life.
Cellular extensions with a large effect
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Tiny extensions on cells, cilia, play an important role in insulin release, according to a new study, which is published in Nature Communications. The researchers report that the cilia of beta cells in the pancreas are covered with insulin receptors and that changed ciliary function can be associated with the development of type 2 diabetes.
NSAIDs prevent colon cancer by inducing death of intestinal stem cells that have mutation
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- Category: Research
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) protect against the development of colorectal cancer by inducing cell suicide pathways in intestinal stem cells that carry a certain mutated and dysfunctional gene, according to a new study led by researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine.
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