Stem cells move one step closer to cure for genetic diseases
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Healthy brain, muscle, eye and heart cells would improve the lives of tens of thousands of people around the world with debilitating mitochondrial diseases. Now, researchers at the Salk Institute have gotten one step closer to making such cures a reality: they've turned cells from patients into healthy, mutation-free stem cells that can then become any cell type.
Therapeutic target identified for treatment of spinal cord injuries
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Spinal cord injuries cause serious functional deficits, including paraplegia or tetraplegia, depending on the scale of the injury. This is due to degeneration of the spinal pathways that carry nerve signals from the brain to the various parts of the body, and vice versa, leading to loss of mobility and sensitivity below the injury.
Scientists identify new compounds that may treat depression rapidly with few side effects
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A new study by researchers at University of Maryland School of Medicine has identified promising compounds that could successfully treat depression in less than 24 hours while minimizing side effects. Although they have not yet been tested in people, the compounds could offer significant advantages over current antidepressant medications.
New technique for precise light-activated chemotherapy drugs
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A new technique that uses light to activate chemotherapy drugs in specific cells shows promise as a way to improve the effectiveness of cancer therapies while preventing severe side effects, according to a study published July 9 in Cell. The so-called photopharmacology approach could be used to treat a broad range of tumors with unprecedented precision simply by making existing cancer drugs sensitive to light - an approach that requires less time and effort compared with traditional drug discovery programs.
Investigators develop activated T cell therapy for advanced melanoma
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T cells from patients with melanoma can trigger a protective immune response against the disease according to a new study out of University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine. Published in the July/August issue of Journal of Immunotherapy, these new findings demonstrate that T cells derived from lymph nodes of patients with melanoma can be expanded in number and activated in the laboratory for intravenous administration in the treatment of patients.
Common hormone could help treat breast cancer
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Around half of all breast cancer patients could one day benefit from having the cheap and widely-available female hormone progesterone added to their treatment, according to Cancer Research UK funded research published in Nature today. Tumours fuelled by the female hormone oestrogen are treated with drugs like tamoxifen to block oestrogen receptors, which cause cancer cells to grow.
Vitamin C related to reduced risk of cardiovascular disease and early death
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New research from the University of Copenhagen and Herlev and Gentofte Hospital shows that high vitamin C concentrations in the blood from the intake of fruit and vegetables are associated with a reduced risk of cardiovascular disease and early death. Fruit and vegetables are healthy. We all know that. And now there is yet another good reason for eating lots of it.
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