World first at the Montreal Heart Institute - personalized therapy for cardiovascular disease
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- Category: Research
Researchers at the Montreal Heart Institute announced today results showing that patients with cardiovascular disease and the appropriate genetic background benefit greatly from the new medication dalcetrapib, with a reduction of 39% in combined clinical outcomes including heart attacks, strokes, unstable angina, coronary revascularizations and cardiovascular deaths.
Blueberries: Small fruit delivers big reward
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Thinking about topping your morning cereal with a cup of blueberries? Just one cup of blueberries per day could be the key to reducing blood pressure and arterial stiffness, both of which are associated with cardiovascular disease. "Our findings suggest that regular consumption of blueberries could potentially delay the progression of prehypertension to hypertension, therefore reducing cardiovascular disease risk,"
An avocado a day keeps the cardiologist away
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Adding an avocado to your daily diet may help lower bad cholesterol, in turn reducing risk for heart disease, according to health researchers. Avocados are known to be a nutrient-dense food, high in monounsaturated fatty acids. Previous studies have suggested that avocados are a cholesterol-lowering food, but this is the first study - to the researchers' knowledge - to look at health implications of avocados beyond monounsaturated fatty acids.
'Glowing' new nanotechnology guides cancer surgery, also kills remaining malignant cells
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Researchers at Oregon State University have developed a new way to selectively insert compounds into cancer cells - a system that will help surgeons identify malignant tissues and then, in combination with phototherapy, kill any remaining cancer cells after a tumor is removed.
Researchers target the cell's 'biological clock' in promising new therapy to kill cancer cells
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Cell biologists at UT Southwestern Medical Center have targeted telomeres with a small molecule called 6-thiodG that takes advantage of the cell's 'biological clock' to kill cancer cells and shrink tumor growth. Dr. Jerry W. Shay, Professor and Vice Chairman of Cell Biology at UT Southwestern, and colleague, Dr. Woodring E. Wright, Professor of Cell Biology and Internal Medicine, found that 6-thio-2'-deoxyguanosine could stop the growth of cancer cells in culture and decrease the growth of tumors in mice.
Nature, nurture and time
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A new study has produced the best evidence yet that the role of genetics in complex traits, including obesity, varies over time. Both the era in which scientific research is conducted and the era in which subjects were born may have an impact on the degree to which genetic factors are present in scientific data.
Researchers map paths to cancer drug resistance
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A team of researchers led by Duke Cancer Institute has identified key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies. By mapping the specific steps that cells of melanoma, breast cancer and a blood cancer called myelofibrosis use to become resistant to drugs, the researchers now have much better targets for blocking those pathways and keeping current therapies effective.
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