A team of researchers led by UNSW Australia scientists has discovered how connections between brain cells are destroyed in the early stages of Alzheimer's disease - work that opens up a new avenue for research on possible treatments for the degenerative brain condition.

Researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai have discovered a key mechanism by which radiation treatment (radiotherapy) fails to completely destroy tumors. And, in the journal Nature Immunology, they offer a novel solution to promote successful radiotherapy for the millions of cancer patients who are treated with it.

University of Notre Dame researchers have discovered a compound that accelerates diabetic wound healing, which may open the door to new treatment strategies. Non-healing chronic wounds are a major complication of diabetes, which result in more than 70,000 lower-limb amputations in the United States alone each year.

In a new study published today in Nature Structural and Molecular Biology, scientists from the University of Surrey have uncovered a collection of important proteins that carry out and regulate critical biological processes. As the malfunctioning of these proteins and processes are linked to diseases such as cancer, their findings could help with the development of more effective therapies for treating incurable and debilitating illnesses.

New research published in The Lancet has shown that a drug, currently used in the treatment of Type II diabetes, can be effective in clearing fatty liver disease from some patients. The researchers from the University of Birmingham believe that the findings present the possibility of new therapies for patients with non-alcoholic fatty liver disease, for which there is no current licensed treatment.

A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, West Africa and in the US, according to a study published in the latest issue of the journal Lancet Infectious Disease.

Despite legal and ethical requirements, information on clinical trials for drugs approved by the U.S. Food and Drug Administration (FDA) varied widely among some of the world's largest drug companies, according to a new study led by a researcher at NYU Langone Medical Center's Division of Medical Ethics in the Department of Population Health.