New drug could be safer, non-addictive alternative to morphine
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- Category: Research
Researchers at Tulane University and Southeast Louisiana Veterans Health Care System have developed a painkiller that is as strong as morphine but isn't likely to be addictive and with fewer side effects, according to a new study in the journal Neuropharmacology.
Ancient medicinal clay shows promise against today's worst bacterial infections
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- Category: Research
Naturally occurring clay from British Columbia, Canada - long used by the region's Heiltsuk First Nation for its healing potential - exhibits potent antibacterial activity against multidrug-resistant pathogens, according to new research from the University of British Columbia.
New mechanism of antitumor action identified
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- Category: Research
A team of UAB (Universitat Autonoma de Barcelona) researchers and collaborators from the Catalan biotech company Ability Pharmaceuticals (UAB Research Park), have described a new mechanism of anti-tumour action, identified during the study and development of the new drug ABTL0812. The study, published in the journal Clinical Cancer Research, was coordinated by Dr José Miguel Lizcano from the UAB Institute of Neurosciences and Department of Biochemistry and Molecular Biology.
New findings may enhance PARP inhibitors therapy in breast cancer
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- Category: Research
Findings from a new study reveal that PARP inhibitors, an emerging class of drugs being studied in cancer clinical trials, may be enhanced by combining them with inhibitors targeting an oncogene known as c-MET which is overexpressed in many cancers.
New particle can track chemo
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Tracking the path of chemotherapy drugs in real time and at a cellular level could revolutionize cancer care and help doctors sort out why two patients might respond differently to the same treatment. Researchers at The Ohio State University have found a way to light up a common cancer drug so they can see where the chemo goes and how long it takes to get there.
'Radiolabeling' lets scientists track the breakdown of drugs
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- Category: Research
A new method for labeling molecules with radioactive elements could let chemists more easily track how drugs under development are metabolized in the body. Chemists consider thousands of compounds in the search for a new drug, and a candidate's metabolism is a key factor that must be evaluated carefully and quickly.
Most top-selling, over-the-counter sexual treatments unproven, some could be harmful
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- Category: Research
From horny goat weed to ginseng and maca, over-the-counter dietary supplements sold to improve male sexual health contain a wide variety of "natural" ingredients. Researchers from Wake Forest Baptist Medical Center reviewed the scientific evidence for the most common ingredients to determine if they are effective - and most importantly - safe.
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