Drug bypasses suppressive immune cells to unleash immunotherapy
- Details
- Category: Research
With a goal of understanding and addressing immunotherapy's limitations, researchers at Washington University School of Medicine in St Louis have found that the immune system can be its own worst enemy in the fight against cancer.
FDA approves new therapy for glioma patients for first time in decades
- Details
- Category: Research
Based on evidence from the INDIGO clinical trial, a global phase 3, double-blinded, randomized clinical trial, vorasidenib more than doubled progression-free survival and delayed the need for treatment with radiation and chemotherapy for patients with Grade 2 IDH-mutant glioma after surgery to remove the tumor.
New biomaterial regrows damaged cartilage in joints
- Details
- Category: Research
Although it looks like a rubbery goo, the material is actually a complex network of molecular components, which work together to mimic cartilage's natural environment in the body.
Proteins as the key to precision medicine: Finding unknown effects of existing drugs
- Details
- Category: Research
AI opens door to safe, effective new antibiotics to combat resistant bacteria
- Details
- Category: Research
Publishing their results in Nature Biomedical Engineering, the scientists describe using a large language model - an AI tool like the one that powers ChatGPT - to engineer a version of a bacteria-killing drug that was previously toxic in humans, so that it would be safe to use.
Drug-chemo combo increases cancer treatment efficacy
- Details
- Category: Research
Previous work has shown that the brain microenvironment has very limited lipids available for cancer cells, making it critical for cancer cells to generate their own lipids to survive.
New drug candidate blocks resistance to cancer therapies
- Details
- Category: Research
Researchers, led by Judith Sebolt-Leopold, Ph.D., discovered MTX-531, a kinase inhibitor with the ability to selectively block both epidermal growth factor receptor (EGFR) and phosphatidylinositol 3-OH kinase (PI3K).
More Pharma News ...
- A new therapeutic target offers a promising pathway for multiple sclerosis treatment
- Chinese medicinal fungus shows promise in treating idiopathic pulmonary fibrosis
- Data from largest clinical trial of pre-symptomatic Alzheimer's disease now widely available
- Fighting antibiotic resistance with peptide cocktails
- Novel drug application shows improved survival for patients with relapsed and refractory acute myeloid leukemia
- Study shows ancient viruses fuel modern-day cancers
- New AI approach optimizes antibody drugs