Alzheimer's disease linked to the metabolism of unsaturated fats
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- Category: Research
A new study published in PLOS Medicine's Special Issue on Dementia has found that the metabolism of omega-3 and omega-6 unsaturated fatty acids in the brain are associated with the progression of Alzheimer's disease. Alzheimer's disease is a neurodegenerative disorder, which causes impaired memory, executive function and language. It accounts for 60 - 80% of total dementia cases worldwide, with over 46 million people suffering from the disease worldwide.
First patient cured of rare blood disorder
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- Category: Research
Using a technique that avoids the use of high-dose chemotherapy and radiation in preparation for a stem cell transplant, physicians at the University of Illinois Hospital & Health Sciences System have documented the first cure of an adult patient with congenital dyserythropoietic anemia. CDA is a rare blood disorder in which the body does not produce enough red blood cells, causing progressive organ damage and early death.
New 'gene silencer' drug reduce cholesterol by over 50 percent
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- Category: Research
The findings come from the largest trial yet to test the safety and effectiveness of this kind of therapy. The technique, known as RNA interference (RNAi) therapy, essentially 'switches off' one of the genes responsible for elevated cholesterol. Researchers from Imperial College London and their colleagues, who conducted the trial, say the twice-a-year treatment could be safely given with or without statins, depending on individual patient needs.
Human antibody for Zika virus promising for treatment, prevention
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- Category: Research
Researchers have determined the structure of a human antibody bound to the Zika virus, revealing details about how the antibody interferes with the infection mechanism - findings that could aid in development of antiviral medications. The new findings also suggest the antibody might be especially effective because a lower concentration than expected is needed to inhibit a key mechanism of infection, making it more potent than previous antibodies studied.
Dietary anti-cancer compound may work by influence on cellular genetics
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- Category: Research
Researchers have discovered one of the reasons why broccoli may be good for your health. They found that sulforaphane, a dietary compound from broccoli that's known to help prevent prostate cancer, may work through its influence on long, non-coding RNAs. This is another step forward in a compelling new area of study on the underlying genetics of cancer development and progression.
Drug combination delivered by nanoparticles may help in melanoma treatment
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- Category: Research
The first of a new class of medication that delivers a combination of drugs by nanoparticle may keep melanoma from becoming resistant to treatment, according to Penn State College of Medicine researchers. CelePlum-777 combines a special ratio of the drugs Celecoxib, an anti-inflammatory, and Plumbagin, a toxin. With the drug, the cells have difficulty overcoming the effect of having more than one active ingredient.
Cooking at home tonight? It's likely cheaper and healthier, study finds
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- Category: Research
Researchers from the University of Washington School of Public Health have been peeking into kitchens - via interviews - for years now. They've just published results showing people who cook at home more often are likely to eat a healthier overall diet. The measurement used to define a healthy diet is called the Healthy Eating Index. It gauges whether a person's diet is giving them the right combination of fruits, vegetables and other elements.
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