Sulforaphane, a phytochemical in broccoli sprouts, ameliorates obesity
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- Category: Research
Sulforaphane, a phytochemical contained in broccoli sprouts at relatively high concentrations, has been known to exert effects of cancer prevention by activating a transcription factor, Nrf2 (nuclear factor (erythroid-derived 2)-like 2), which regulates the balance of oxidation - reduction in the cell, and by enhancing anti-oxidation ability of the body and detoxication of chemical compounds taken into the body.
How molecular machines may drive the future of disease detection and drug delivery
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- Category: Research
University of Alberta scientists have pulled into the lead in a race to use nanomachines for improved disease detection and drug delivery in patients. In a study published in Nature Communications, the researchers describe the creation of synthetic DNA motors in living cells. The process - previously only successful in test tubes - demonstrates how DNA motors can be used to accomplish specific and focused biological functions in live cells.
Volkswagen's excess emissions will lead to 1,200 premature deaths in Europe
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- Category: Research
In September 2015, the German Volkswagen Group, the world's largest car producer, admitted to having installed "defeat devices" in 11 million diesel cars sold worldwide between 2008 and 2015. The devices were designed to detect and adapt to laboratory tests, making the cars appear to comply with environmental standards when, in fact, they emitted pollutants called nitric oxides, or NOx, at levels that were on average four times the applicable European test-stand limit.
Scientists stimulate immune system, stop cancer growth
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- Category: Research
Researchers at the University of Illinois at Chicago report that increasing expression of a chemical cytokine called LIGHT in mice with colon cancer activated the immune system's natural cancer-killing T-cells and caused primary tumors and metastatic tumors in the liver to shrink.
Inhaler users get about half as much medicine as they should from each puff
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- Category: Research
Tens of millions of Americans with lung disease use metered-dose inhalers each day, and new studies by Rice University electrical engineers and pulmonologists at Baylor College of Medicine have identified critical errors that are causing many inhaler users to get only about half as much medicine as they should from each puff.
Molecule stops fatal pediatric brain tumor
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- Category: Research
The scientists have found a molecule that stops the growth of an aggressive pediatric brain tumor. The tumor is always fatal and primarily strikes children under 10 years old. Every year, about 300 children under the age of 10 years old in the U.S. develop a tumor referred to as diffuse intrinsic pontine glioma (DIPG).
Alzheimer's drug prescribed off-label could pose risk for some
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- Category: Research
Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test. UCLA School of Nursing researchers discovered that for people who carry a specific genetic variation - the K-variant of butyrylcholinesterase, or BChE-K - donezpezil could accelerate cognitive decline.
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