Danish discovery can pave the way for more effective cholesterol medicine
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More than 600,000 Danes are being treated with cholesterol lowering medicine. 98 per cent of them are treated with statins, which curb the body's own production of cholesterol so that the level of cholesterol falls. However, statins also give rise to the body forming more of a harmful protein - known as PCSK9 - which counters the effect of the statins.
Scientists find way to convert bad body fat into good fat
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There's good fat and bad fat in our bodies. The good fat helps burn calories, while the bad fat hoards calories, contributing to weight gain and obesity. Now, new research at Washington University School of Medicine in St. Louis has identified a way to convert bad, white fat into good, brown fat, at least in mice.
Beta blockers not needed after heart attack if other medications taken
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A new study from the University of North Carolina at Chapel Hill finds beta blockers are not needed after a heart attack if heart-attack survivors are taking ACE inhibitors and statins. The study is the first to challenge the current clinical guideline that heart-attack survivors should take all three drugs - beta blockers, ACE inhibitors and statins - for the rest of their lives.
Cells programmed like computers to fight disease
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Cells can be programmed like a computer to fight cancer, influenza, and other serious conditions - thanks to a breakthrough in synthetic biology by the University of Warwick. Led by Professor Alfonso Jaramillo in the School of Life Sciences, new research has discovered that a common molecule - ribonucleic acid (RNA), which is produced abundantly by humans, plants and animals - can be genetically engineered to allow scientists to program the actions of a cell.
'Exciting' discovery on path to develop new type of vaccine to treat global viruses
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Scientists at the University of Southampton have made a significant discovery in efforts to develop a vaccine against Zika, dengue and Hepatitis C viruses that affect millions of people around the world. In a study published in Science Immunology, researchers have shown that natural killer cells (NK cells), which are a fundamental part of the body's immune system, can recognise many different viruses including global pathogens such as Zika, dengue and Hepatitis C viruses, through a single receptor called KIR2DS2.
Protein research could help in hunt for Alzheimer's and Parkinson's cures
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Research carried out at the University of Kent has the potential to influence the future search for treatment of neurodegenerative diseases that are linked to a family of protein molecules known as 'amyloid'. The findings by a team of scientists led by Dr Wei-Feng Xue in the School of Biosciences could lead to a better understanding of the diseases, and suggest potential diagnostics and therapeutics strategies to combat amyloid-associated disease progression and their possible infectivity.
Immunotherapy combination safe and 62 percent effective in metastatic melanoma patients
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Immunotherapy is a promising approach in the treatment of metastatic melanoma, an aggressive and deadly form of skin cancer; but for most patients, immunotherapy drugs so far have failed to live up to their promise and provide little or no benefit. In a phase 1b clinical trial with 21 patients, researchers tested the safety and efficacy of combining the immunotherapy drug pembrolizumab with an oncolytic virus called T-VEC.
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