Palm oil in your Valentine's chocolate?
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- Category: Research
A diet rich in saturated fat and sugar not only leads to obesity, it creates inflammation in the nucleus accumbens, a part of the brain that controls mood and reward. And this inflammation leads to depressive, anxious and compulsive behaviours associated with metabolic dysfunction and obesity, according to a new study by researchers at the University of Montreal Hospital Research Centre (CRCHUM).
Light-activated cancer drugs without toxic side effects: fresh insight
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- Category: Research
Future cancer drugs that are activated by light and don’t cause the toxic side-effects of current chemotherapy treatments are closer to becoming a reality, thanks to new research made possible by the Monash Warwick Alliance, an intercontinental collaboration between the University of Warwick (UK) and Monash University (Australia).
Using injectable self-assembled nanomaterials for sustained delivery of drugs
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- Category: Research
Because they can be programmed to travel the body and selectively target cancer and other sites of disease, nanometer-scale vehicles called nanocarriers can deliver higher concentrations of drugs to bombard specific areas of the body while minimizing systemic side effects. Nanocarriers can also deliver drugs and diagnostic agents that are typically not soluble in water or blood as well as significantly decrease the effective dosage.
Chinese researchers report first lung stem cell transplantation clinical trial
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- Category: Research
A research team from Tongji University in China have made a breakthrough in human lung regeneration technology. For the first time, researchers have regenerated patients' damaged lungs using autologous lung stem cell transplantation in a pilot clinical trial. The study can be found in the open access journal Protein & Cell which is published by Springer Nature.
How old antibiotic compounds could become tomorrow's life-saving drugs
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- Category: Research
As the fight against drug-resistant infections continues, University of Leeds scientists are looking back at previously discarded chemical compounds, to see if any could be developed for new antibiotics. In the heyday of antibiotic development in the mid-20th century many different chemical compounds with antibacterial properties were examined, but only a small proportion were selected for development into drugs.
Guidelines extended to improve the use of feedback from patients in clinical trials
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- Category: Research
Researchers have recommended changes to international guidelines used in the development of clinical trials in an effort to gain information about the impact of the treatment on participating patients and their quality of life. Protocols describe how a clinical trial will be conducted, including its objectives, design, methodology, statistical considerations and organisation, and ensures the safety of participating patients as well as the integrity of the data collected.
New research suggests your immune system can protect against MRSA infections
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- Category: Research
After years of investigation, researchers at Johns Hopkins, the University of California, Davis, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph). The findings, publishing online in The Journal of Clinical Investigation, open new doors to someday developing vaccines to prevent staph skin infections, which account for 14 million outpatient visits, nearly 500,000 hospital admissions and $3 billion to $4 billion in inpatient health care costs in the U.S. per year.
More Pharma News ...
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- Drug trial protocol redactions by industry sponsors exposed
- Repurposed drug found to be effective against Zika virus
- More stroke patients may receive crucial treatments under new guideline
- Cells of 3 advanced cancers die with drug-like compounds that reverse chemo failure