New targeted therapy schedule could keep melanoma at bay
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- Category: Research
Skin melanoma, a particularly insidious cancer, accounts for the vast majority skin cancer deaths and is one of the most common cancers in people under 30. Treatment for advanced melanoma has seen success with targeted therapies - drugs that interfere with division and growth of cancer cells by targeting key molecules - especially when multiple drugs are used in combination. While the combination of targeted therapies improves patient outcomes, any remaining cancer cells can lead to drug resistance.
First proof a synthesized antibiotic is capable of treating superbugs
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- Category: Research
A "game changing" new antibiotic which is capable of killing superbugs has been successfully synthesised and used to treat an infection for the first time - and could lead to the first new class of antibiotic drug in 30 years. The breakthrough is another major step forward on the journey to develop a commercially viable drug version based on teixobactin - a natural antibiotic discovered by US scientists in soil samples in 2015 which has been heralded as a "gamechanger" in the battle against antibiotic resistant pathogens such as MRSA and VRE.
North and south cooperation to combat tuberculosis
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- Category: Research
Tuberculosis can be cured and could be eradicated. For this to happen, however, patients have to receive the right treatment. Researchers at the Makerere University and the University of Zurich were able to demonstrate that the levels of medication used are often too low. As a result, patients remained contagious with the dangerous disease for longer than necessary.
Medicating for mental health
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- Category: Research
Weight gain and Type 2 diabetes are potential side effects in people taking a common medication to treat mental illness. Now a new University of Guelph study has revealed that a single bout of intense exercise performed right before taking a dose of olanzapine could be a way to prevent these side effects.
Medical expansion has improved health - with one exception
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- Category: Research
While Americans debate the rising cost of health care, a new study of 30 countries over 27 years found that medical expansion has improved overall health - with one major exception. Researchers found that increased spending on health care and increases in specialized care were both associated with longer life expectancy and less mortality in the countries studied. But pharmaceutical industry expansion was linked to negative health effects.
Stem cells treat macular degeneration
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- Category: Research
In July 2015, 86-year-old Douglas Waters developed severe age-related macular degeneration (AMD). He struggled to see things clearly, even when up close. A few months later, he became part of a clinical trial that used stem cell-derived ocular cells developed in part by researchers at UC Santa Barbara. His retinal eyepatch was implanted at Moorfields Eye Hospital, a National Health Service (NHS) facility in Waters' hometown of London, England.
Medicinal cannabis is safe and effective - it's time to reboot research
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- Category: Research
Medicinal cannabis is safe and effective in pain relief, and researchers are calling for the treatment to be properly established in our modern medical arsenal. A new special issue of the European Journal of Internal Medicine provides a comprehensive overview of current evidence for the use of cannabis and derived products in medicine, and calls for more research to improve the evidence base for its use.
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- Surprise finding could lead to new MS treatments
- Many clinical trial status discrepancies identified between ClinicalTrials.gov and EUCTR
- Drug-producing bacteria possible with synthetic biology breakthrough