New technique for precise light-activated chemotherapy drugs
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- Category: Research
A new technique that uses light to activate chemotherapy drugs in specific cells shows promise as a way to improve the effectiveness of cancer therapies while preventing severe side effects, according to a study published July 9 in Cell. The so-called photopharmacology approach could be used to treat a broad range of tumors with unprecedented precision simply by making existing cancer drugs sensitive to light - an approach that requires less time and effort compared with traditional drug discovery programs.
Investigators develop activated T cell therapy for advanced melanoma
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- Category: Research
T cells from patients with melanoma can trigger a protective immune response against the disease according to a new study out of University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine. Published in the July/August issue of Journal of Immunotherapy, these new findings demonstrate that T cells derived from lymph nodes of patients with melanoma can be expanded in number and activated in the laboratory for intravenous administration in the treatment of patients.
Common hormone could help treat breast cancer
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- Category: Research
Around half of all breast cancer patients could one day benefit from having the cheap and widely-available female hormone progesterone added to their treatment, according to Cancer Research UK funded research published in Nature today. Tumours fuelled by the female hormone oestrogen are treated with drugs like tamoxifen to block oestrogen receptors, which cause cancer cells to grow.
Vitamin C related to reduced risk of cardiovascular disease and early death
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- Category: Research
New research from the University of Copenhagen and Herlev and Gentofte Hospital shows that high vitamin C concentrations in the blood from the intake of fruit and vegetables are associated with a reduced risk of cardiovascular disease and early death. Fruit and vegetables are healthy. We all know that. And now there is yet another good reason for eating lots of it.
Discovery points to a new path toward a universal flu vaccine
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- Category: Research
Flu vaccines can be something of a shot in the dark. Not only must they be given yearly, there's no guarantee the strains against which they protect will be the ones circulating once the season arrives. New research by Rockefeller University scientists and their colleagues suggests it may be possible to harness a previously unknown mechanism within the immune system to create more effective and efficient vaccines against this ever-mutating virus.
The BMJ's data sharing policy now applies to all clinical trials
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- Category: Development
From 1st July 2015 The BMJ requires sharing of individual patient data for all clinical trials. This means that trials will be considered for publication only if the authors agree to make the relevant anonymised patient level data available on reasonable request. The BMJ is the first general medical journal to require data sharing for all trials,
Citrus fruit consumption may be associated with increased melanoma risk
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- Category: Research
A new analysis of dietary patterns among more than 100,000 Americans suggests that frequent consumption of citrus - namely whole grapefruit and orange juice - may be associated with an increased risk of melanoma. Melanoma risk was 36% higher in people who consumed citrus fruit or juice at least 1.6 times daily compared to those who consumed them less than twice per week.
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