Cheating death: How cancer cells escape
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- Category: Research
Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.
US prescription drug prices are 2.78 times those in other wealthy nations
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- Category: Development
Prescription drug prices in the U.S. are significantly higher than in other nations, with prices in the U.S. averaging 2.78 times those seen in 33 other nations, according to a new RAND report.
The gap between prices in the U.S. and other countries is even larger for brand-named drugs, with U.S. prices averaging 4.22 times those in comparison nations.
Nanotechnology-based CRISPR/Cas9 delivery system for genome editing in cancer treatment
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- Category: Research
This review is designed by Professor Changyang Gong and written by his PhD student Shiyao Zhou. At the beginning, they elaborated the mechanism of CRISPR/Cas9 system. CRISPR/Cas9 system consists of Cas9 protein and single stranded directing RNA (sgRNA). In the presence of protospacer adjacent motif (PAM), sgRNA accurately leads the Cas9 endonuclease to the target regions, where it causes DNA double strand breaks (DSBs), resulting in site‐specific genomic change.
Up to three daily servings of kimchi may lower men's obesity risk
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- Category: Research
Eating up to three daily servings of the Korean classic, kimchi, may lower men's overall risk of obesity, while radish kimchi is linked to a lower prevalence of midriff bulge in both sexes, finds research published in the open access journal BMJ Open.
Kimchi is made by salting and fermenting vegetables with various flavourings and seasonings, such as onion, garlic, and fish sauce.
New technology makes cancer easier for immune system to find and destroy
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- Category: Research
A new technology to increase visibility of cancer cells to the immune system using CRISPR has been developed, and could lead to a new way to treat cancer.
Major histocompatibility complex (MHC) class I molecules are an immune complex present on the surface of all cells in humans. MHC class I molecules are a prerequisite for the immune system to recognize and eliminate cancer.
'Cancer-cooling' protein puts bowel cancer on ice
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- Category: Research
A protein in the immune system can be manipulated to help overcome bowel cancer, according to new research from The Australian National University (ANU).
Bowel cancer claims more than 100 lives in Australia each week, yet around 90 per cent of cases can be successfully treated if detected early.
Autonomous synthesis robot uses AI to speed up chemical discovery
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- Category: Research
Chemists of the University of Amsterdam (UvA) have developed an autonomous chemical synthesis robot with an integrated AI-driven machine learning unit. Dubbed 'RoboChem', the benchtop device can outperform a human chemist in terms of speed and accuracy while also displaying a high level of ingenuity. As the first of its kind, it could significantly accelerate chemical discovery of molecules for pharmaceutical and many other applications.
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