Since the acquisition agreement was announced in January, integration teams at Pfizer and Wyeth have worked diligently to ensure that the combined company is fully operational immediately upon the closing of the transaction. To further advance these objectives, Pfizer previously announced a new approach to research and development and an enhanced commercial operating structure, and named select leaders to posts that became effective upon closing of the acquisition. As a result of these actions, Pfizer will begin to capitalize on the benefits offered by the combination with Wyeth starting immediately. "Our ability to close this transaction in such a timely manner and be operational on 'Day One' is a true testament to the dedication of the integration teams at both companies," said Pfizer Chief Financial Officer Frank D'Amelio, who is leading the integration. "Because business continuity was our primary objective throughout the integration process, our leaders and colleagues are in a position to quickly build on Pfizer's solid financial foundation, operational discipline and diverse product base to continue to improve our performance." Strengthened and Diversified Portfolio
Pfizer now has a broad and diversified global product portfolio, with leadership in virtually all key high-growth therapeutic areas. The combined company has strengthened capabilities in biotechnology, vaccines, consumer healthcare, nutrition and animal health. Pfizer is well positioned for consistent and stable top-line and adjusted diluted EPSi growth over the short and long term. It is expected that no drug will account for more than 10 percent of the combined company's revenue in 2012. The combined company has a robust and growing pipeline of biopharmaceutical development projects to help patients in critical areas, including Alzheimerâs disease, oncology, pain, neuroscience, diabetes and inflammation. The combination of top scientists from both companies, as well as leading scientific and manufacturing capabilities, and a global network of proof-of-concept clinical development centers, has greatly enhanced the company's ability to innovate. Flexible, Patient-Centric Global Operating Structure
Pfizer will now operate through its patient-centric business units in human health as well as through its animal health, consumer and nutrition businesses that match the speed and agility of small, focused enterprises with the benefits of a global organization's scale and resources. These businesses are organized into two groups to allow their leadership to identify opportunities and address challenges that exist across the business units and better align corporate priorities. The Biopharmaceuticals Business units are Emerging Markets, Established Products, Oncology, Primary Care and Specialty Care, which includes vaccines. The Diversified Businesses are Animal Health, Capsugel, Consumer Healthcare and Nutrition. Pfizer also now has two distinct research and development organizations to maximize new opportunities in biopharmaceutical research. The PharmaTherapeutics Research & Development group focuses on the discovery of small molecules and related modalities, and the BioTherapeutics Research & Development group focuses on large-molecule research, including vaccines. The individual units within these two research organizations are led by world-class Chief Scientific Officers, who act as single points of accountability for delivering positive proofs-of-concept for Pfizer's businesses to develop. Pfizer also now has a significantly strengthened global footprint in the United States, Europe, Asia and Latin America, and has an enhanced ability to help patients in key emerging markets such as China and the Middle East. Leadership
Pfizer's Executive Leadership Team, which represents a combination of Pfizer and Wyeth leaders, includes:
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Jeffrey B. Kindler - Chairman & Chief Executive Officer
Frank D'Amelio - Chief Financial Officer, Senior Vice President, Business Operations
Mikael Dolsten - President, BioTherapeutics Research & Development
Freda Lewis-Hall - Senior Vice President, Chief Medical Officer
Martin Mackay - President, PharmaTherapeutics Research & Development
Mary McLeod - Senior Vice President, Human Resources
Ian Read - Group President, Worldwide Biopharmaceutical Businesses
Cavan Redmond - Group President, Diversified Businesses
Nat Ricciardi - President, Manufacturing
Bill Ringo - Senior Vice President, Business Development, Strategy & Innovation
Amy Schulman - Senior Vice President, General Counsel
Sally Susman - Senior Vice President, Chief Communications Officer
The acquisition is expected to be accretive to Pfizer's adjusted diluted earnings per share1 in the second full year after closing. The transaction is anticipated to yield synergies of approximately $4 billion by the end of 2012. These synergies, which are in addition to the approximately $2 billion in net annual cost savings that we plan to achieve by the end of 2011 apart from the Wyeth acquisition, are expected in selling, informational and administrative functions, research and development, and manufacturing. Pfizer Inc: Working together for a healthier world™
At Pfizer, we apply science and our global resources to improve health and well-being at every stage of life. We strive to set the standard for quality, safety and value in the discovery, development and manufacturing of medicines for people and animals. Our diversified global health care portfolio includes human and animal biologic and small molecule medicines and vaccines, as well as nutritional products and many of the world's best-known consumer products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as the world's leading biopharmaceutical company, we also collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on us. To learn more about our commitments, please visit us at www.pfizer.com. Wyeth is now a wholly owned subsidiary of Pfizer Inc. The merger of local Wyeth and Pfizer entities may be pending in various jurisdictions and integration is subject to completion of various local legal and regulatory obligations. More information is available at www.pfizer.com.