Scientists finally confirm vitamin B1 hypothesis from 1958
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The molecule in question is a carbene, a type of carbon atom with only six valence electrons. Generally, carbon is stable with eight electrons around it. With only six electrons, it is chemically unstable and highly reactive.
Empowering antibodies to better activate the immune system
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Their results, described April 22, 2025 in Cell Reports, indicate that a higher ratio of antibodies to viral protein - in this case, a part of HIV - better engages two specific types of immune cells.
BlueRock Therapeutics announces publication in Nature of 18-month data from Phase 1 clinical trial for bemdaneprocel, an investigational cell therapy for Parkinson's disease
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"The concept of "rebuilding" brain networks that have been lost to disease is compelling," said Claire Henchcliffe, MD, chair of the UC Irvine School of Medicine's Department of Neurology at the University of California, Irvine and one of the study's Principal Investigators,
Existing drug has potential for immune paralysis
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Study finds pinworm medication has potential to treat aggressive skin cancer
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Merkel cell carcinoma is a rare but fast-growing neuroendocrine cancer that is three to five times more likely than melanoma to be deadly.
Scientists achieve record-breaking growth in miniature, functional liver models
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Popular diabetes medications, including GLP-1 drugs, may protect against Alzheimer's disease
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In research published in JAMA Neurology on April 7, UF researchers studied Medicare claims data of older adults with Type 2 diabetes to assess the association among glucagon-like peptide-1 receptor agonists, or GLP-1RAs, sodium-glucose cotransporter-2 inhibitors, or SGLT2is, and the risk of Alzheimer's disease and related dementias.
Potential treatment for Parkinson's using investigational cell therapy shows early promise
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The treatment involved creating nerve cells (neurons) derived from embryonic stem cells and transplanting them into the brains of 12 Parkinson's patients.
Researchers develop an LSD analogue with potential for treating schizophrenia
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The research, published in Proceedings of the National Academy of Sciences, highlights the new drug's potential as a treatment option for conditions like schizophrenia, where psychedelics are not prescribed for safety reasons.
The gut health benefits of sauerkraut
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Authors Maria Marco, professor with the Department of Food Science and Technology, and Lei Wei, a postdoctoral researcher in Marco's lab, looked at what happens during fermentation - specifically, how the metabolites in sauerkraut compared to those in raw cabbage.